The practice of insufflating alprazolam, a benzodiazepine commonly known by a specific brand name, involves crushing the tablets and inhaling the resulting powder through the nasal passages. This method of administration differs significantly from oral ingestion, which is the prescribed route.
Individuals may choose this route of administration based on the perception of a faster onset of effects compared to swallowing the medication. The nasal mucosa allows for quicker absorption into the bloodstream, potentially intensifying the initial euphoric feelings or sedative properties. However, this rapid absorption also carries significant risks, including increased potential for overdose, addiction, and damage to the nasal passages. The historical context surrounding benzodiazepine misuse highlights a pattern of individuals seeking to amplify or accelerate the drug’s effects, often disregarding the associated health consequences.