The commercially available formulation of minoxidil marketed towards men contains a higher concentration of the active ingredient than the version intended for women. This difference in concentration is a primary factor in the product’s gender-specific labeling. Using the higher concentration can lead to adverse effects in women that are less common or less severe when using the lower concentration formula.
Minoxidil’s initial development was as an oral medication for high blood pressure. One of the observed side effects was hair growth, which led to its topical application for treating hair loss. The concentration difference between the men’s and women’s formulations reflects a careful balancing of efficacy and risk, acknowledging that women may be more susceptible to certain side effects at higher doses. These side effects can include unwanted hair growth on the face and other body areas, as well as potential cardiovascular effects.
