9+ Safe Restart: Antiplatelet After SDH?

when to restart antiplatelet after subdural hematoma

9+ Safe Restart: Antiplatelet After SDH?

Resuming antiplatelet therapy following a subdural hematoma presents a complex clinical decision-making scenario. The decision hinges on balancing the risk of recurrent hemorrhage against the potential for thromboembolic events, particularly in patients with underlying cardiovascular or cerebrovascular disease. Considerations include the size and stability of the hematoma, the patient’s overall risk profile, and the indication for antiplatelet medication.

The avoidance of thromboembolic complications is a primary concern in patients requiring antiplatelet agents. Premature cessation can lead to significant morbidity and mortality. However, restarting such medications too early after a subdural hematoma increases the risk of rebleeding and subsequent neurological deterioration. Historically, management was often conservative, involving prolonged antiplatelet discontinuation, but more recent data suggest earlier resumption may be considered in carefully selected patients.

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9+ Tips: When to Restart SGLT2 After Surgery?

when to restart sglt2 inhibitor after surgery

9+ Tips: When to Restart SGLT2 After Surgery?

Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a class of medications used primarily in the management of type 2 diabetes. They function by reducing glucose reabsorption in the kidneys, leading to increased glucose excretion in the urine and subsequently lowering blood glucose levels. Because surgical procedures can significantly alter metabolic status and fluid balance, a careful evaluation is necessary to determine the appropriate time to resume these medications post-operatively. This decision involves assessing factors such as glycemic control, renal function, and the patients overall clinical stability after the procedure.

The judicious management of antidiabetic medications around surgical interventions is critical to minimizing the risk of complications. Continuing SGLT2 inhibitors perioperatively can increase the potential for diabetic ketoacidosis (DKA), particularly in the absence of significantly elevated blood glucose levels, a condition known as euglycemic DKA. Conversely, abruptly discontinuing these medications may lead to hyperglycemia and other metabolic disturbances. Therefore, carefully considering the risks and benefits is essential for optimizing patient outcomes.

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