The initial breakout period, sometimes referred to as the “purge,” represents a common, albeit unwelcome, phase during isotretinoin treatment. This phenomenon involves a temporary exacerbation of acne symptoms, characterized by an increase in the number of pimples, blackheads, and whiteheads on the skin’s surface. For example, an individual with moderate acne may experience a significant increase in inflammatory lesions during this phase before seeing improvement.
Understanding the temporal aspect of this initial breakout is important for patient adherence and managing expectations. It allows dermatologists to counsel patients effectively, minimizing anxiety and encouraging them to continue with the prescribed treatment regimen. Historically, recognizing this potential worsening of acne has been crucial in preventing premature discontinuation of the medication, ensuring individuals receive the full therapeutic benefit.